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Staff Picks: Wake Forest vs Clemson

Who will win, Wake Forest or Clemson? Read our staff picks for this electric matchup here!

Staff| September 23, 2022 (Updated: July 9, 2025)
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#5 Clemson has a big test this week as they head to Winston Salem to face #21 Wake Forest in an ACC matchup. The Tigers have had bumps on offense and will face a challenge against a solid Deacons defense. Sam Hartman will play in his second game this year, giving the home team a shot to win. Below are the Mike Farrell Sports picks for this week four matchup.


Mike Farrell- Clemson

The Tigers should win this game on the road by one score.


Cory Lemer- Clemson

DJ Uiagalelei will get benched when the Tigers fall behind early, but freshman Cade Klubnik will lead Clemson to a comeback win.


Matt Perkins- Wake Forest

Coach Dabo Swinney will finally switch QBs after Wake Forest leads by 17. It will not be enough, and Wake Forest will win in a close game. Cade Klubnik will impress, leading to him being named the starter.


Timothy Bailey- Clemson

Both teams are opposites. The Tigers rely on defense, while Wake Forest relies on offense. Clemson will win in a close game.


Unnamed source- Wake Forest

Sam Hartman is a top-three QB in all of college football. While the Clemson defense is far better than the Wake defense, Wake has the best player in this game. I expect this game to be close, but I think the team with the better QB will ultimately pull away late. Will Shipley will give the Clemson offense a realistic chance, but the Wake offense is far more explosive. The excellent, new mix-in of RPOs and tempo makes the Deacon offense elite. Clemson will not escape Winston-Salem with a win. Give me the Demon Deacons, 37-27!


Luke Brumm-Wake Forest

Wake Forest will pull off the upset behind an electric home crowd.

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Kyle Golik-Clemson

This game will be a QB duel won by either DJ or Cade.


James DeCarlo- Clemson

I like Dabo and the Tigers to expose this Wake Forest defense.


Paul Wangsmo- Clemson

Wake Forest struggles on defense, allowing the Tigers to take advantage and win on the road.


Noah Dzik- Wake Forest

Wake Forest will win in a close low, scoring affair in Winston-Salem.


Shayne Pickering- Clemson

Sam Hartman coming back is huge for Wake Forest; however, the raw talent of Clemson will prevail.


Alex Bryan- Wake Forest

Sam Hartman is the key to this game. I think he can succeed against the Tiger’s defense. I’ll take Wake Forest 34-27.


Hunter DeNote- Wake Forest

This game is intriguing, and I like Wake Forest to upset Clemson at home. 

Category: Game PreviewTag: Cade Klubnik, Clemson, Dabo Swinney, Dave Clawson, DJ Uiagalelei, Khalil Taylor, Wake Forest, Will Shipley
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